The post-market environmental monitoring of GM maize in the EU has a limited capacity to identify adverse effects


Abstract The EU legislation requests post-market environmental monitoring (PMEM) of a genetically modified (GM) organism even if its pre-market risk assessment indicated negligible risks. It has been claimed that the monitoring of the only currently commercially cultivated GM plant in the EU, Bt MON810 …

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In-depth comparative toxicogenomics of glyphosate and Roundup herbicides: histopathology, transcriptome and epigenome signatures, and DNA damage


By Robin Mesnage, Mariam Ibragim, Daniele Mandrioli, Laura Falcioni, Fiorella Belpoggi, Inger Brandsma, Emma Bourne, Emanuel Savage, Charles A Mein, Michael N Antoniou doi: https://doi.org/10.1101/2021.04.12.439463 Conclusions Taken together, the results of our study show that Roundup herbicides are more toxic than glyphosate, activating mechanisms …

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Trans-disciplinary diagnosis for an in-depth reform of regulatory expertise in the field of environmental toxicology and security


By: Joël Spiroux de Vendômois, Jean-Paul Bourdineaud, Arnaud Apoteker, Nicolas Defarge, Emilie Gaillard, Corinne Lepage, Jacques Testart & Christian Vélot Published in: Toxicological Research (2021) Abstract: Repeated health and environmental scandals, the loss of biodiversity and the recent burst of chronic diseases constantly remind …

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Improved strategies to counter the COVID-19 pandemic: Lockdowns vs. primary and community healthcare


COVID-19 pandemic mitigation strategies are mainly based on social distancing measures and healthcare system reinforcement. However, many countries in Europe and elsewhere implemented strict, horizontal lockdowns because of extensive viral spread in the community which challenges the capacity of the healthcare systems. However, strict …

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Book publication: Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts


ENSSER members Robin Mesnage, András Székács, Michael Antoniou and Nicolas de Sadeleer have contributed to this book: Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts addresses contemporary debates on herbicide toxicology. The reader is offered a comprehensive overview of this complex topic, presented by internationally …

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Facing the 2020 pandemic: What does cyberbiosecurity want us to know to safeguard the future?


by Siguna Müller published in Elsevier’s Biosecurity and Health: https://doi.org/10.1016/j.bsheal.2020.09.007   Abstract As the entire world is under the grip of the coronavirus diseases 2019 (COVID-19), and as many are eagerly trying to explain the origins of the virus and cause of the pandemic, …

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Why did EFSA not reduce its ADI for aspartame or recommend its use should no longer be permitted?


by Erik Paul Millstone and Elisabeth Dawson published in Archives of Public Health: https://archpublichealth.biomedcentral.com/articles/10.1186/s13690-020-00489-w Abstract On behalf of the European Food Safety Authority (EFSA), Kass and Lodi recently published a letter purporting to ‘refute’ our July 2019 analysis of EFSA’s December 2013 assessment of …

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IAASTD+10: ten years on from the largest agricultural assessment ever


In 2009, ca. 400 authors contributed to the unique “International Assessment of Agricultural Knowledge, Science and Technology for Development” (IAASTD). Now, a group of former authors and review editors of the IAASTD, including two ENSSER members, Jack Heinemann and Angelika Hilbeck, decided to commemorate …

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Geocentrism vs genocentrism: theories without metaphors, metaphors without theories


by Giuseppe Longo and Matteo Mossio Published in Interdisciplinary Science Reviews ABSTRACT Through the comparison between two major, long-lasting theoretical frameworks – geocentrism and genocentrism – we discuss the different epistemological role played by metaphors in physics and biology. Throughout its history, physics developed …

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Stacked genetically modified soybean harboring herbicide resistance and insecticide rCry1Ac shows strong defense and redox homeostasis disturbance after glyphosate-based herbicide application


by Caroline Bedin Zanatta, Rafael Fonseca Benevenuto, Rubens Onofre Nodari & Sarah Zanon Agapito-Tenfen published in Environmental Sciences Europe volume 32, Article number: 104 (2020) View the full article and download the pdf   Abstract Background World agricultural production of genetically modified (GM) products, in particular, the …

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Timing is everything: Survival of Atlantic salmon Salmo salarpostsmolts during events of high salmon lice densities


by Thomas Bøhn| Karl Øystein Gjelland| Rosa M. Serra-Llinares| Bengt Finstad|Raul Primicerio| Rune Nilsen| Ørjan Karlsen| Anne D. Sandvik| Ove T. Skilbrei|Kristine Marit S. Elvik| Øystein Skaala| Pål A. Bjørn DOI: 10.1111/1365-2664.13612 Abstract 1. Atlantic salmon in aquaculture act as reservoir hosts and vectors …

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Broadening the GMO risk assessment in the EU for genome editing technologies in agriculture


By Katharina Kawall, Janet Cotter & Christoph Then Environmental Sciences Europe volume 32, Article number: 106 (2020)   Abstract Genome editing techniques, especially the CRISPR/Cas technology, increase the possibilities and the speed of altering genetic material in organisms. So-called genome editing is increasingly being …

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Italian Documentary on the origins of SARS-CoV-2 with interview of molecular geneticist Dr Michael Antoniou


Documentary by the Italian journalist Paolo Barnard with an interview with the molecular geneticist Dr Michael Antoniou about the possibility that SARS-CoV-2, the virus that causes COVID-19, is a genetically engineered creation that escaped from a lab. The interview was published on Youtube: https://www.youtube.com/watch?v=3WQp2Aqr1ps …

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Confusing biological rhythms and physical clocks – Today’s ecological relevance of Bergson-Einstein debate on time


Abstract The reflections on the nature of time in Relativity Theory will be hinted in reference to the new bridges recently proposed by Connes and by Rovelli’s “perspectival” approach, two major steps towards a unification of quantum, thermodynamical and relativistic times. The so called …

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Genetic engineering endangers the protection of species


Genetic engineering endangers the protection of species Subtitle: Why the spread of genetically engineered organisms into natural populations has to be prevented Autor(s): Christoph Then This report is primarily concerned with the consequences of genetic engineering interventions into evolutionary processes. Leading scientists working in …

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New scientific study highlights non-monotonic dose-response curves and low-dose effects of bisphenol A


Maël Montévil, Nicole Acevedo, Cheryl M. Schaeberle, Manushree Bharadwaj, Suzanne E. Fenton, and Ana M. Soto published a paper in the context of the Clarity BPA study that is significant for current debates on the regulation of endocrine disruptor, and that you might find …

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The Story behind COVID-19: Animal Diseases at the Crossroads of Wildlife, Livestock and Human Health


Article on the impacts of viruses on wildlife, livestock and human health   Prof J Godfroid and Prof N de Sadeleer published an article (special issue on Covid in the European Journal of Risk Regulation) on the zoonotic origin of COVID-19 and, generally speaking, …

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GMO regulations and their interpretation: how EFSA’s guidance on risk assessments of GMOs is bound to fail


The article “GMO regulations and their interpretation: how EFSA’s guidance on risk assessments of GMOs is bound to fail” by Angelika Hilbeck, Hartmut Meyer, Brian Wynne & Erik Millstone, published in Environmental Sciences Europe volume 32, Article number: 54 (2020) may be viewed here …

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Spatio‐temporal controllability and environmental risk assessment of genetically engineered gene drive organisms from the perspective of EU GMO Regulation


The article by Dr Christoph Then, Dr Katharina Kawall, and Dr Nina Valenzuelawas published on 6 April 2020 in the  journal Integrated Environmental Assessment and Management of the Society of Environmental Assessment and Management. Please find the abstract here: https://setac.onlinelibrary.wiley.com/doi/abs/10.1002/ieam.4278 Please find the article …

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Overview of genome editing applications using SDN-1 and SDN-2 in regard to EU regulatory issues


Brochure by TestBiotech Authors: Katharina Kawall, Juliana Miyazaki, Andreas Bauer-Panskus, Christoph Then Overview of genome editing applications using SDN-1 and SDN-2 in regard to EU regulatory issues – New methods of genetic engineering (genome editing) and their potential impact on nature protection and the …

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Risk assessment of genetically engineered plants that can persist and propagate in the environment


Risk assessment of genetically engineered plants that can persist and propagate in the environment. By Andreas Bauer-Panskus, Katharina Kawall, Juliana Miyazaki, Christoph Then AND: Rendering of the sustainable pulse.


Just published: GMOs and ROUNDUP: Similar long term toxicities due to glyphosate formulations


JUST PUBLISHED – February 2020 ​VIENT DE PARAÎTRE – Février 2020 (in french below) GMOs AND ROUNDUP: SIMILAR LONG TERM TOXICITIES DUE TO GLYPHOSATE FORMULATIONS Glyphosate is associated with carcinogenic petroleum additives and heavy metals in pesticides (formulations, which are always mixtures). This penetrates and bioaccumulates …

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Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway


Robin Mesnage, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Quinten Raymond Ducarmon, Romy Daniëlle Zwittink , Caroline Amiel, Jean-Michel Panoff, Fiorella Belpoggi , Michael N Antoniou https://www.biorxiv.org/content/10.1101/870105v1.full.pdf Abstract: There is intense debate as to whether glyphosate can interfere with aromatic amino acid biosynthesis in microorganisms …

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The Introduction of Thousands of Tonnes of Glyphosate in the food Chain—An Evaluation of Glyphosate Tolerant Soybeans


by Thomas Bøhn and Erik Millstone Foods 2019, 8(12), 669; https://doi.org/10.3390/foods8120669 Abstract: Glyphosate-tolerant (GT) soybeans dominate the world soybean market. These plants have triggered increased use of, as well as increased residues of, glyphosate in soybean products. We present data that show farmers have …

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Insufficient risk assessment of herbicide-tolerant genetically engineered soybeans intended for import into the EU


By: Juliana Miyazaki, Andreas Bauer-Panskus, Thomas Bøhn, Wolfram Reichenbecher & Christoph Then Published: Environmental Sciences Europe volume 31, Article number: 92 (2019) DOI https://doi.org/10.1186/s12302-019-0274-1   Abstract The introduction of herbicide-tolerant (HT) genetically engineered (GE) soybeans has raised new challenges for the European risk assessment …

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Review: Limitations in the evidential basis supporting health benefits from a decreased exposure to pesticides through organic food consumption


By Robin Mesnage, Ioannis N. Tsakiris, Michael N. Antoniou, Aristides Tsatsakis https://doi.org/10.1016/j.cotox.2019.11.003 Abstract Consumer demand for organic food is mostly based on the belief that organic products are healthier because they are less contaminated with pesticides. We explain why health benefits from a decreased …

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Paper: EFSA’s toxicological assessment of aspartame: was it even-handedly trying to identify possible unreliable positives and unreliable negatives?


A new paper of Erik Millstone et al. has been published in Archives of Public Health. A copy of the paper is attached below, along with copies of two appendices.   A dossier of supporting documentation is available. The paper and appendices are available on …

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Laboratory tests with Lepidoptera to assess non-target effects of Bt maize pollen: analysis of current studies and recommendations for a standardised design


By Andreas Lang, Marina Lee, Matthias Dolek, Julitta Berchtold and Mathias Otto   Abstract: Background and approach: Common standards for laboratory studies of non-target organisms are recognised as prerequisite to assist the risk assessments regarding the evaluation of environmental effects of transgenic crops. Here, …

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Press Release: New study: Herbicides (glyphosate, dicamba) & antibiotic resistance


A new study finds that bacteria develop antibiotic resistance up to 100,000-times faster when exposed to the world’s most widely used herbicides, Roundup (glyphosate) and Kamba (dicamba) and antibiotics compared to without the herbicide. This study adds to a growing body of evidence that …

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Comment by Ricarda Steinbrecher on Kyrou et al 2018 in Nature Biotechnology: Gene drives breakthrough needs urgent restraint


A research development that crashed a population of caged mosquitoes could enable elimination of non-target species, says Dr Ricarda Steinbrecher Gene drive researchers associated with Target Malaria and funded by US DARPA, the GATES Foundation and the UK BBSRC have just managed to crash …

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Report – Gene-edited organisms in agriculture: risks and unexpected consequences


In recent years, there has been much discussion of how gene editing techniques, such as CRISPR, can broaden the scope of genetic engineering in agriculture. However, it’s becoming clear that gene editing techniques are error prone. This new report from Friends of the Earth …

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Estimating acute mortality of Lepidoptera caused by the cultivation of insect-resistant Bt maize – The LepiX model


Article by LorenzFahse, Phillip Papastefanou, and Mathias Otto   Abstract The cultivation of Bt maize, genetically modified to be resistant to insect pests, has led to intense scientific and political debate about its possible adverse impacts on biodiversity. To better address this question we …

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Study: Impacts of glyphosate-based herbicides on disease resistance and health of crops: a review


By Daisy A. Martinez, Ulrich E. Loening, and Margaret C. Graham.   Abstract: Based on experimental data from laboratory and field, numerous authors have raised concern that exposure to glyphosate-based herbicides (GBHs) may pre-dispose crops to damage by microbial pathogens. In this review, we …

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Chemical Pesticides and Human Health: The Urgent Need for a New Concept in Agriculture


By Polyxeni Nicolopoulou-Stamati1*, Sotirios Maipas1, Chrysanthi Kotampasi1, Panagiotis Stamatis1 and Luc Hens2 1 Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, 2 Vlaamse Instelling voor Technologisch Onderzoek (VITO), Mol, Belgium doi: 10.3389/fpubh.2016.00148 Published in 2016 in frontiers in …

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