Robin Mesnage

Terrestrial ecotoxicity of glyphosate, its formulations, and co-formulants: evidence from 2010–2023

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By Szandra Klátyik, Gergely Simon, Marianna Oláh, Robin Mesnage, Michael N. Antoniou, Johann G. Zaller & András Székács Environmental Sciences Europe volume 35, Article number: 51 (2023) https://enveurope.springeropen.com/articles/10.1186/s12302-023-00758-9   Abstract Glyphosate (GLY), the most widely used herbicide in the world, is frequently detected in various environmental matrices, including soil, the foundation of agriculture. In practice, … Read more

Genotoxicity Assays Published since 2016 Shed New Light on the Oncogenic Potential of Glyphosate-Based Herbicides

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By Charles Benbrook, Robin Mesnage and William Sawyer Agrochemicals 2023, 2(1), 47-68 https://www.mdpi.com/2813-3145/2/1/5 Abstract: Controversy over the oncogenicity of glyphosate-based herbicides (GBHs) persists seven years after a 2015 IARC Monograph classified glyphosate/GBHs as “probably carcinogenic” to humans. Most regulatory authorities have concluded that technical glyphosate poses little or no oncogenic risk via dietary exposure. The … Read more

Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts

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The book Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts addresses contemporary debates on herbicide toxicology. Edited by Robin Mesnage and Johann Zaller and including contributions from Michael Antoniou, Nicolas de Sadeleer and András Székács, a strength of this book is its multidisciplinarity. Internationally recognized experts in different domains (toxicology, ecosystem health, agriculture, chemistry, regulation and … Read more

In-depth comparative toxicogenomics of glyphosate and Roundup herbicides: histopathology, transcriptome and epigenome signatures, and DNA damage

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By Robin Mesnage, Mariam Ibragim, Daniele Mandrioli, Laura Falcioni, Fiorella Belpoggi, Inger Brandsma, Emma Bourne, Emanuel Savage, Charles A Mein, Michael N Antoniou doi: https://doi.org/10.1101/2021.04.12.439463 Conclusions Taken together, the results of our study show that Roundup herbicides are more toxic than glyphosate, activating mechanisms involved in cellular carcinogenesis and causing gene expression changes reflecting DNA … Read more

Groundbreaking Glyphosate-Microbiome Study

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Glyphosate and the glyphosate-based herbicide Roundup disrupt the gut microbiome by the same mechanism by which the chemical acts as a weedkiller, and these effects happen even at low doses that regulators claim to be safe, a newly published study has found. The new study was conducted by an international team of scientists based in … Read more

Book publication: Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts

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ENSSER members Robin Mesnage, András Székács, Michael Antoniou and Nicolas de Sadeleer have contributed to this book: Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts addresses contemporary debates on herbicide toxicology. The reader is offered a comprehensive overview of this complex topic, presented by internationally recognized experts. Information presented will inform discussions on the use of … Read more

Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

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Robin Mesnage, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Quinten Raymond Ducarmon, Romy Daniëlle Zwittink , Caroline Amiel, Jean-Michel Panoff, Fiorella Belpoggi , Michael N Antoniou https://www.biorxiv.org/content/10.1101/870105v1.full.pdf Abstract: There is intense debate as to whether glyphosate can interfere with aromatic amino acid biosynthesis in microorganisms inhabiting the gastrointestinal tract, which could potentially lead to negative health … Read more

Review: Limitations in the evidential basis supporting health benefits from a decreased exposure to pesticides through organic food consumption

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By Robin Mesnage, Ioannis N. Tsakiris, Michael N. Antoniou, Aristides Tsatsakis https://doi.org/10.1016/j.cotox.2019.11.003 Abstract Consumer demand for organic food is mostly based on the belief that organic products are healthier because they are less contaminated with pesticides. We explain why health benefits from a decreased exposure to pesticides through organic food consumption remain unsubstantiated. There is … Read more

Long list of glyphosate concerns shows EC flouts precautionary principle

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PR 01/16 Long list of glyphosate concerns shows EC flouts precautionary principle A group of fourteen experts, including ENSSER member Michael Antoniou and CRIIGEN[i] member Robin Mesnage, warns that current safety assessments of glyphosate based herbicides (GBHs) as well as their maximum daily intake limits are based on outdated science. Also, exposure levels have risen … Read more

The world-wide dominant herbicide contains compounds more toxic than expected as new research shows

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PR 01/13 The world-wide dominant herbicide contains compounds more toxic than expected as new research shows Zusatzstoffe des weltweit bedeutendsten Herbizids sind deutlich toxischer als erwartet – Jüngste Forschungsergebnisse aus Frankreich publiziert Le principal herbicide du monde contient des substances plus toxiques que prevu – une nouvelle recherche le demontre Una nueva investigatión demuestra que … Read more