MRNA vaccines

Cross-Priming and Cross-Tolerance After Intramuscular mRNA Vaccination for Viral Infections: Feasibility and Implications

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By Siguna Mueller Center for Research in Medical Pharmacology, University of Insubria, 21100 Varese, Italy Life2025, 15(10), 1575; https://doi.org/10.3390/life15101575 Abstract The induction of robust CD8 T cell immunity after intramuscular (i.m.) mRNA vaccination has remained a challenge. Due to the limited presence of professional antigen-presenting cells (APCs) in muscle tissue, this route of administration tends … Read more

Existing and emerging mRNA vaccines and their environmental impact: a transdisciplinary assessment

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By Siguna Mueller Environmental Sciences Europe volume 36, Article number: 144 (2024) Abstract mRNA vaccines have played a massive role during the COVID-19 pandemic and are now being developed for numerous other human and animal applications. Nevertheless, their potential ramifications on the environment lack scrutiny and regulation. On 14 July 2020, the EU decided to temporarily exclude the … Read more